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2/18 Sleep Disruption in Neurodivergent People Part 2

Updated: Nov 8, 2025

Neurodivergent people (including those with ADHD, autism, dysautonomia, PTSD, migraine, and chronic illness) experience sleep disruption at much higher rates than the general population. But it’s not just bad habits — it’s neurobiology.

This week, DNA is revisiting one of our most requested topics: how the neurodivergent brain experiences sleep differently — and what science says about why.


We’ll discuss:

  • The neurobiology of sleep and arousal — how the hypothalamus, brainstem, and autonomic nervous system interact to “switch off” the brain

  • Dysregulated circadian rhythms in neurodivergent populations (melatonin secretion delays, “night owl” wiring, and why blue light hits harder)

  • Hyperarousal and sensory overstimulation — why silence or stillness can actually feel unsafe to the neurodivergent nervous system

  • Co-existing medical factors: pain, POTS, mast cell activation, and cortisol spikes

  • Why conventional advice (“no screens, meditate”) often fails, and what actually helps

  • Evidence-based interventions: behavioral pacing, light therapy, magnesium glycinate, body-temperature regulation, and CBT-I for neurodivergent brains


Grounded in research:

  • Wajszilber et al. (2018) Sleep in ADHD: A Systematic Review and Meta-Analysis – Sleep Medicine Reviews

  • Baker et al. (2019) Circadian rhythm and insomnia in autism spectrum disorder – Biological Psychiatry

  • Mathias & Low (2018) Autonomic dysfunction in chronic illness and sleep disruption – Clinical Autonomic Research

  • Horne (2022) Cortisol awakening response and neurodivergent stress patterns – Neurobiology of Sleep and Circadian Rhythms


 
 

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